The following are declared to be part of the Limpopo Province Disease Management Area:
| (i) | The northern boundary is the international border between the Nwanedi river and the Kruger National Park fence, while the eastern boundary is the Kruger National Park fence; |
| (ii) | The portion of Musina local municipality east of the Nwanedi River; |
| (iii) | The whole of Thulamela local municipality; |
| (iv) | The whole of Collins Chabane local municipality; |
| (v) | The portions of Greater Giyani local municipality and Greater Letaba local municipality which lies east of the D3206 and north of the Mooketsi / Giyani Road (R81) to where the R81 road crosses Little Letaba River and from there north of the Little Letaba River up to the fence of the KNP. |
